Tuesday, August 18, 2009

HORMONE RECEPTOR



A hormone receptor is a receptor protein on the facade of a cell that binds to a definite hormone. The hormone grounds various changes to take place in the cell. Binding of hormones to hormone receptors frequently generate the start of a biophysical sign that can direct to supplementary signal transduction pathways, or prompt the activation or inhibition of genes.

There are two
types of Hormone Receptors:

Steroid hormone receptors and associated receptors are normally soluble proteins that function during gene activation. Their response elements are DNA sequences that are bound by the multipart of the steroid bound to its receptor. The receptors themselves are zinc-finger proteins. These receptors include those for glucocorticoids, androgens, estrogen, thyroid hormone (T3), the active form of vitamin D which is the calcitriol, and the retinoids.

Peptide hormone receptors are often transmembrane proteins. They are as well termed as sensory receptor, G-protein-coupled receptors, or ionotropic receptors. These receptors commonly function via intracellular second messengers, together with cyclic AMP, the calcium (Ca2+)-calmodulin system and the inositol 1,4,5-trisphosphate (IP3).



REFERENCE/s:
Principles of Human Anatomy and Physiology by G. Tortora
http://www.bio-balance.com/
http://en.wikipedia.org/wiki/Hormone_receptor

3 comments:

Virginia Gaces said...

Good entry. Read more for class presentation.

zorlone said...

It must be my fondness of pictures, I am actually looking for one in this post.

Well researched! Of course, if you really want to read more, you can find journals online.

Z

Luke said...

Cells really are complex, aren't they? And you did a good job explaining this receptor thing. :)